Publications by authors named "R P Baer"
Purpose: Administrative data sources are used to describe the epidemiology of chronic hypertension in pregnancy and its consequences. Differences in identification across sources may affect research estimates. We compared identification of chronic hypertension in birth certificate records, hospital discharge records, and Medi-Cal claims in the same individuals.
View Article and Find Full Text PDFBackground: Population-based databases are valuable for perinatal research. The California Department of Health Care Access and Information (HCAI) created a linked birth file covering the years 1991 through 2012. This file includes birth and fetal death certificate records linked to the hospital discharge records of the birthing person and infant.
View Article and Find Full Text PDFArticle Synopsis
- Metastatic melanoma often avoids current treatments that trigger cell death through apoptosis, suggesting the need for therapies that target different cell-death pathways.
- Doramectin, previously effective in neuroblastoma by promoting autophagy, was tested on B16F10 melanoma cells to see if it induces similar effects.
- Results revealed that doramectin decreased cell growth and caused apoptotic characteristics in melanoma cells, but increased autophagy wasn't detected, leading to the conclusion that doramectin may offer a new mechanism for inducing cell death in melanoma treatment.
Article Synopsis
- Preterm birth (PTB) is a significant cause of infant health issues in the US, influenced by racial, ethnic, and socioeconomic disparities, indicating a need for further research to understand risk factors.
- Over the past decade, a study analyzed singleton live births in California to examine PTB rates among various racial and ethnic groups and insurance types, finding notable variations.
- The overall PTB rate increased from 6.8% to 7.5% between 2011 and 2022, with the rates varying significantly among different racial groups, showing higher rates in Black individuals with public insurance compared to White individuals with nonpublic insurance.
Importance: Sudden infant death syndrome (SIDS) is a major cause of infant death in the US. Previous research suggests that inborn errors of metabolism may contribute to SIDS, yet the relationship between SIDS and biomarkers of metabolism remains unclear.
Objective: To evaluate and model the association between routinely measured newborn metabolic markers and SIDS in combination with established risk factors for SIDS.