Publications by authors named "R Ottridge"
Article Synopsis
- People with Parkinson's disease often have speech problems, affecting how they talk and interact with others.
- The PD COMM trial tested two types of therapy to help with these speech issues: one is called Lee Silverman Voice Treatment LOUD, and the other is regular speech therapy from the National Health Service.
- The study took place in the UK and involved different groups of participants, comparing the effectiveness and cost of each therapy method against doing nothing.
Article Synopsis
- - The ROCkeTS study aimed to find the best diagnostic test for ovarian cancer in symptomatic postmenopausal women by comparing multiple risk-prediction models in a real-world setting.
- - Researchers recruited women aged 16-90 with non-specific symptoms and abnormal test results from 23 UK hospitals, excluding those with certain conditions like normal CA125 levels or other cancers.
- - The study involved various diagnostic models and tests, including CA125 levels and ultrasound assessments, to evaluate their effectiveness in predicting ovarian cancer risk among the participants.
Objective: Symptom-triggered testing for ovarian cancer was introduced to the UK whereby symptomatic women undergo an ultrasound scan and serum CA125, and are referred to hospital within 2 weeks if these are abnormal. The potential value of symptom-triggered testing in the detection of early-stage disease or low tumor burden remains unclear in women with high grade serous ovarian cancer. In this descriptive study, we report on the International Federation of Gynecology and Obstetrics (FIGO) stage, disease distribution, and complete cytoreduction rates in women presenting via the fast-track pathway and who were diagnosed with high grade serous ovarian cancer.
View Article and Find Full Text PDFBackground: Estimation of glomerular filtration rate using equations based on creatinine is widely used to manage chronic kidney disease. In the UK, the Chronic Kidney Disease Epidemiology Collaboration creatinine equation is recommended. Other published equations using cystatin C, an alternative marker of kidney function, have not gained widespread clinical acceptance.
View Article and Find Full Text PDFObjectives: To assess the clinical effectiveness of two speech and language therapy approaches versus no speech and language therapy for dysarthria in people with Parkinson's disease.
Design: Pragmatic, UK based, multicentre, three arm, parallel group, unblinded, randomised controlled trial.
Setting: The speech and language therapy interventions were delivered in outpatient or home settings between 26 September 2016 and 16 March 2020.