Publications by authors named "R Othman"
Introduction: Type 2 diabetes (T2D) is a prevalent metabolic disorder linked to chronic inflammation and endothelial dysfunction, which contributes to the development of microvascular complications (MVCs) such as diabetic retinopathy (DR) and diabetic neuropathy (DN). Genetic factors, including variations in the ABO gene, may influence these complications. This study aimed to investigate the association between the ABO rs2073823 polymorphism and the risk of MVCs in patients with T2D, as well as its impact on inflammatory biomarkers, endothelial markers, and lipid profiles.
View Article and Find Full Text PDFBackground: High-density lipoprotein (HDL) protects against myocardial ischemia-reperfusion (I/R) injury. Mammalian target of rapamycin complexes 1 and 2 (mTORC1 and mTORC2) play opposing roles in protecting against I/R injury, whereby mTORC1 appears to be detrimental while mTORC2 is protective. However, the role of HDL and mTORC signaling in protecting against I/R in hypertensive rodents is not clearly understood.
View Article and Find Full Text PDFArticle Synopsis
- This text discusses the importance of intersectional approaches in climate policy to address the unique health impacts of climate change on women, girls, and gender-diverse individuals, who often face compounded vulnerabilities due to systemic oppression.
- It highlights the lack of meaningful gender and health representation in international climate governance, emphasizing that despite some progress, men still dominate decision-making roles in climate policy.
- The text advocates for promoting gender-responsiveness in climate strategies to enhance inclusivity and effectiveness, leading to more resilient and equitable societies.