Publications by authors named "R Otero-Candelera"
Background: Risk of VTE recurrence (VTEr) in patients with cancer-associated thrombosis (CAT) is high. Cancer-related risk factors for VTEr have been studied, but information about the importance of location of metastasis is scarce.
Objectives: 1) Evaluate rate of VTEr in CAT patients according to location of metastasis, and 2) Identify variables associated to VTEr during long-term follow-up.
Article Synopsis
- The study investigates the impact of residual venous thrombosis (RVT) on the risk of recurrent venous thromboembolism (VTE) in patients with cancer-associated thrombosis (CAT) over a 15-year span.
- Out of 511 patients, 35.8% had RVT at 6 months, with associations found between RVT and factors like ECOG performance status, metastasis, and cancer location.
- Results indicated that RVT at 6 months doubles the risk of recurrent VTE within 5 years, while no significant link was found between RVT and clinically relevant bleeding.
Article Synopsis
- Pulmonary hypertension (PH) is a complex condition that can benefit from mobile health apps for better management and education for both patients and healthcare professionals.
- A study evaluated the quality of free smartphone apps available for PH, searching through app stores in 2022 and 2023, resulting in the identification of 21 apps.
- While the overall quality scores were acceptable, the majority of apps focused on providing general PH information and none involved patient input during development, highlighting a potential gap in user-centric design.
Background: Patients with cancer-associated thrombosis (CAT) face a heightened risk of clinically relevant bleeding (CRB). However, the relationship between these risks and the location of metastasis remains unclear.
Methods: A single-center, non-interventional study of consecutive patients was conducted between 2007 and 2022, involving patients with CAT (n = 1,277).
Article Synopsis
- Detecting hidden cancers in patients with unexplained venous thromboembolism (VTE) is challenging, and this study sought to explore how coagulation-related biomarkers could help.
- A study involving 214 patients with unprovoked VTE measured several biomarkers at diagnosis, finding that sP-selectin levels were significantly higher in patients with occult cancer.
- Combining high levels of sP-selectin and D-dimer can potentially identify occult cancer with up to 91% specificity, indicating these biomarkers may be useful in clinical settings, although more research is needed.