Publications by authors named "R Omranipour"
Neoadjuvant Endocrine Therapy Compared to Neoadjuvant Chemotherapy in Node-Positive HR+, HER2- Breast Cancer (Nodal pCR and the Rate of ALND): A Systematic Review and Meta-Analysis.
Breast J
January 2025
Article Synopsis
- Patients with HR+, HER2- breast cancers have lower responses to neoadjuvant therapy, and this study examines the effectiveness of neoadjuvant endocrine therapy (NET) in these patients.
- A total of 18,037 patients participated in the study, with 3,707 receiving NET and 14,330 receiving neoadjuvant chemotherapy (NAC), with NET patients being older on average (64.1 vs. 47.6 years).
- Results showed that node pathologic complete response (pCR) rates were 8.9% for NET compared to 14.9% for NAC, and axillary lymph node dissection (ALND) rates were also lower for NET patients (39.1%
Purpose: We aimed to examine the importance of an lncRNA, namely LINC00852, in the pathogenesis of breast cancer.
Materials And Methods: In the current study, we used several online tools to examine the importance of LINC00852 in breast cancer. Then, we examined these findings in 50 pairs of breast cancer tissues and adjacent non-cancerous ones.
Background & Objective: Antigen Ki-67 (histone-based nuclear protein) is a static marker of tumor cell proliferation and growth and is commonly measured to indicate the effect of treatment in breast cancer patients. This single-arm trial study aimed to evaluate the effect of short-term endocrine therapy (letrozole) on Ki-67 levels in menopausal women with early hormone-positive breast cancer who were referred to two university hospitals.
Methods: Patients with a pre-treatment Ki67 of 5% or less were excluded from the study.
Background: Breast cancer (BC) treatment decreases fertility capacity, but unnecessary fertility preservation procedures in women who would not be infertile after treatment would be a waste of time and resources and could cause the unwarranted exposure of cancer cells to exogenous sex hormones. It has been largely shown that post-treatment ovarian reserve is directly associated with pre-treatment anti-mullerian hormone levels (AMH0). A threshold for AMH0, or a model including AMH0 and patient characteristics that could distinguish the patients who will be infertile after treatments, still needs to be defined.
View Article and Find Full Text PDFBackground: Stress is an overwhelming feeling in patients with breast cancer (BC). However, The effect of virtual education has not been fully regulated. Hence, this study intends to compare the impact of 2 virtual education methods on perceived stress and stress coping in women with BC.
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