We present PepFuNN, a new open-source version of the PepFun package with functions to study the chemical space of peptide libraries and perform structure-activity relationship analyses. PepFuNN is a Python package comprising five modules to study peptides with natural amino acids and, in some cases, sequences with non-natural amino acids based on the availability of a public monomer dictionary. The modules allow calculating physicochemical properties, performing similarity analysis using different peptide representations, clustering peptides using molecular fingerprints or calculated descriptors, designing peptide libraries based on specific requirements, and a module dedicated to extracting matched pairs from experimental campaigns to guide the selection of the most relevant mutations in design new rounds.
View Article and Find Full Text PDF, or "mamey sapote", is a tropical fruit tree native to Central America and Southern Mexico, producing sweet, nutrient and vitamin-rich fruit. Several insect pests are known to infest but none have been associated with plant growth alterations. Eriophyoid mites are well known to cause plant malformations, but mites that cause this type of damage to mamey sapote have not been reported.
View Article and Find Full Text PDFTransmission of plant viruses that replicate in the insect vector is known as persistent-propagative manner. However, it remains unclear whether such virus-vector relationships also occur between plant viruses and other biological vectors such as arthropod mites. In this study, we investigated the possible replication of orchid fleck virus (OFV), a segmented plant rhabdovirus, within its mite vector (Brevipalpus californicus s.
View Article and Find Full Text PDFThe genus Ultratenuipalpus (Acariformes: Tenuipalpidae) is represented by 26 species worldwide. We describe and illustrate Ultratenuipalpus dicranopteris sp. nov.
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