Publications by authors named "R O Fisch"
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus. Advancing age leads to a decline in neurogenesis, which is associated with impaired cognition. The cellular mechanisms causing reduced neurogenesis with advancing age remain largely unknown.
View Article and Find Full Text PDFObjective: To use American Board of Urology (ABU) case log data to elucidate practice patterns for benign prostatic hyperplasia (BPH) surgery. Several surgical modalities have been introduced in recent decades causing significant practice variation.
Materials And Methods: We retrospectively analyzed ABU case logs from 2008-2021 to assess trends in BPH surgery.
Article Synopsis
- This study focused on a holistic genetic evaluation of patients with immune-related issues, recognizing that multiple genetic factors might contribute to their health conditions rather than just a single gene explanation.
- Researchers analyzed genetic data from 1505 individuals, uncovering 361 molecular diagnoses linked to various immune presentations, with significant updates obtained through reanalysis and new gene discoveries.
- The findings indicate that the majority of molecular diagnoses could inform treatment options, highlighting the potential for whole exome analysis to enhance our understanding of genetic contributions to health on a large scale.
Heat-bath Monte Carlo simulations have been used to study a 12-state discretized Heisenberg model with a type of random field on simple cubic lattices of size 128×128×128. The 12 states correspond to the [110] directions of a cube. The model has the standard nonrandom two-spin exchange term with coupling energy J and a random field which consists of adding an energy h_{R} to two of the 12 spin states, chosen randomly and independently at each site.
View Article and Find Full Text PDFClenched fist injury is associated with a high risk of infectious complications and is commonly managed with formal irrigation and debridement in the operating theatre. The purpose of this study was to determine outcomes associated with irrigation and debridement of clenched fist injuries under local anaesthesia using field sterility outside the operative theatre. In this single centre study, 232 patients were identified with clenched fist injury and 210 were treated with a standard protocol beginning with administration of intravenous antibiotics and then irrigation and debridement at the bedside.
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