Publications by authors named "R Nolen-Walston"
Bilateral diaphragmatic paralysis in a weanling donkey jack.
J Vet Emerg Crit Care (San Antonio)
December 2024
Objective: To describe the clinical presentation and diagnosis of bilateral diaphragmatic paralysis in a weanling miniature donkey jack.
Case Summary: A 5-month-old miniature donkey jack presented to a tertiary care facility for fever, cough, and increased respiratory rate and effort initially unresponsive to treatment with antimicrobials and anti-inflammatories. Clinical and diagnostic evaluations found no evidence of upper respiratory obstruction or bacterial pneumonia.
Article Synopsis
- Bronchoalveolar lavage (BAL) is a procedure used to assess inflammation in horse lungs, but the exact time it takes for inflammation to resolve post-BAL is unclear.
- A study involving six healthy horses tested the hypothesis that inflammation would resolve by 72 hours after BAL, using a cross-over design with multiple BALs at different time intervals.
- Results showed no significant inflammation at 72 and 96 hours; macrophage levels increased, but overall significant lung inflammation was not present, indicating BAL can be safely repeated after 72 hours.
Background: Leukergy is the phenomenon of aggregation of leukocytes on a peripheral blood film, and in humans, it is used as an indicator of systemic inflammation and infection.
Objectives: To assess the association of leukergy on blood film examination with biochemical and clinical evidence of systemic inflammation, infection, neoplasia, or specific organ system disease.
Methods: A case-control study using retrospective analysis (2017-2022) identified all canine and feline patients that had been presented to an academic referral center with a finding of leukergy on peripheral blood film and an equal number of species-matched controls.