A Randomized Controlled Trial on the Effect of Luseogliflozin on Bone Microarchitecture Evaluated Using HR-pQCT in Elderly Type 2 Diabetes.

Introduction: Bone fragility is a critical issue in the treatment of elderly people with type 2 diabetes (T2D). In the Canagliflozin Cardiovascular Assessment Study, the subjects with T2D who were treated with canagliflozin showed a significant increase in fracture events compared to a placebo group as early as 12 weeks post-initiation. In addition, it has been unclear whether sodium-glucose co-transporter 2 (SGLT2) inhibitors promote bone fragility.

Chemotherapy effects on bone mineral density and microstructure in women with breast cancer.

Introduction: Chemotherapy involves the administration of steroids to prevent nausea and vomiting; however, its effect on bone microstructure remains unknown. This study aimed to evaluate the changes in bone mineral density (BMD) and bone microstructure associated with chemotherapy using high-resolution peripheral quantitative computed tomography (HR-pQCT) in women with early breast cancer.

Materials And Methods: This prospective single-arm observational study included non-osteoporotic, postmenopausal women with breast cancer.

Auditory scene context facilitates visual recognition of objects in consistent visual scenes.

Visual object recognition is facilitated by contextually consistent scenes in which the object is embedded. Scene gist representations extracted from the scenery backgrounds yield this scene consistency effect. Here we examined whether the scene consistency effect is specific to the visual domain or if it is crossmodal.

The contributions of surface features and contour shapes to object slant perception.

Humans perceive 3D shapes even from 2D images. A slant can be perceived from images of slanted rectangular objects, which include texture gradients and linear perspective contours. How does the visual system integrate and utilize these pictorial depth cues? A new visual illusion that provides some insights into this issue was examined.

Good conduct makes your face attractive: The effect of personality perception on facial attractiveness judgments.

Human facial attractiveness is related to physical features, such as clear complexion and symmetry. However, it is also known that facial attractiveness judgments are influenced by a wide range of non-physical factors. Here, we examined the effect of the personality information of a target person on facial attractiveness judgments.