Publications by authors named "R Nigro"

The objective was to evaluate the effect of material (four monolithic zirconia) and surface condition [glazed (G) versus polished after simulation of occlusal adjustment (GAP)] on roughness and volumetric wear (VW) of dental zirconia after chewing simulation (CS). Zirconia specimens (ZS) were fabricated with an approximate diameter of 12.0 mm and a thickness of 1.

View Article and Find Full Text PDF

Alginate is a natural polysaccharide commonly obtained from brown algae and is usually used in the food industry as an additive, specifically as a thickening, gelling, and emulsifying agent. Due to its polyanionic nature, it can crosslink in the presence of divalent or trivalent cations. This crosslinking process involves the formation of chemical bonds between the carboxylic groups of parallel chains, resulting in a solid structure.

View Article and Find Full Text PDF

Recently, the role of the gut microbiota in metabolic health, immunity, behavioral balance, longevity, and intestine comfort has been the object of several studies from scientific communities. They were encouraged by a growing interest from food industries and consumers toward novel fermented ingredients and formulations with powerful biological effects, such as pre, pro, and postbiotic products. Depending on the selected strains, the operating conditions, the addition of suitable reagents or enzymes, the equipment, and the reactor configurations, functional compounds with high bioactivity, such as short-chain fatty acids, gamma-aminobutyric acid, bioactive peptides, and serotonin, can be enhanced and/or produced through fermentation of several vegetable matrices.

View Article and Find Full Text PDF

The advancement of anti-cancer therapies has markedly improved the survival rate of children with cancer, making them long-term childhood cancer survivors (CCS). Nevertheless, these treatments cause a low-grade inflammatory state, determining inflamm-aging and, thus, favoring the early onset of chronic diseases normally associated with old age. Identification of novel and safer therapeutic strategies is needed to counteract and prevent inflamm-aging.

View Article and Find Full Text PDF
Article Synopsis
  • SGLT2 inhibitors are increasingly used for managing diabetes and have additional benefits for kidney function and heart health.
  • Despite their advantages, they can cause complications like euglycemic ketoacidosis, which is a serious condition.
  • In a reported case, a 47-year-old patient developed ketoacidosis after 5 years on SGLT2 therapy, and successful resolution was achieved using somatostatin alongside standard treatment.
View Article and Find Full Text PDF