Publications by authors named "R Nicholas Staab"
Article Synopsis
- Loss-of-function mutations in a specific gene linked to dystonia reveal similarities to idiopathic dystonia, highlighting the gene's role in regulating cAMP levels in the striatum, a brain region critical for movement.
- Researchers developed a genetic mouse model to study the effects of knocking out this gene in a targeted manner, observing significant motor impairments and dystonic behaviors in these mice.
- The findings indicate that the loss of this gene increases the excitability of certain neurons, suggesting that reducing this hyperexcitability could lead to potential treatments for both genetic and idiopathic forms of dystonia.
With increasing mpox cases in Maricopa County, Arizona, the county's health department launched a survey on July 11, 2022, to gather eligibility and contact data and provide clinic information to those interested in JYNNEOS as postexposure prophylaxis (PEP) or expanded postexposure prophylaxis(PEP++). Survey data were matched to case and vaccination data. Overall, 343 of the 513 respondents (66.
View Article and Find Full Text PDFObjective: To examine the impact of our new rapid refeeding protocol on patients with anorexia nervosa (AN) in our Eating Disorders Program. We hypothesize that the new protocol would lead to a more rapid weight gain and a shorter length of stay, with no effect on medical complications or program completion.
Method: This cohort design included consecutive inpatients and day hospital patients admitted to the program with a BMI <18 kg/m and a diagnosis of AN between 2007 and 2020; N = 326 patients.
Background: Anorexia nervosa is characterised by a chronic course that is refractory to treatment in many patients and has one of the highest mortality rates of any psychiatric disorder. Deep brain stimulation (DBS) has been applied to circuit-based neuropsychiatric diseases, such as Parkinson's disease and major depression, with promising results. We aimed to assess the safety of DBS to modulate the activity of limbic circuits and to examine how this might affect the clinical features of anorexia nervosa.
View Article and Find Full Text PDF