Effect of plateletpheresis on donor variables and platelet yield using three different cell separators: Experience from tertiary care hospital.

Introduction: Platelet collection by apheresis is common nowadays. Many cell separators are available in the market for the same. This study was conducted to study the effect of various donor factors on platelet yield and the effect of different cell separator variables on platelet yield.

Stable Antifouling and Antibacterial Coating Based on Assembly of Copper-Phenolic Networks.

Biofilm formation on medical devices has become a worldwide issue arising from its resistance to bactericidal agents and presenting challenges to eradicating biofouling adhesion, especially in biological fluids. Metal-phenolic networks have been demonstrated as a versatile and efficient strategy to prevent biofilm formation by endowing medical devices with prolonged antifouling and antibacterial activities in a one-step surface modification. In this study, we report a simple and environmentally friendly method using coordination chemistry between copper ions (Cu) and dopamine-containing copolymer to fabricate metal-phenolic network-based coatings.

Forcing the code: tension modulates signaling to drive morphogenesis and malignancy.

Development and disease are regulated by the interplay between genetics and the signaling pathways stimulated by morphogens, growth factors, and cytokines. Experimental data highlight the importance of mechanical force in regulating embryonic development, tissue morphogenesis, and malignancy. Force not only sculpts tissue movements to drive embryogenesis and morphogenesis but also modifies the context of biochemical signaling and gene expression to regulate cell and tissue fate.

Temperature-Responsive Injectable Composite Hydrogels Based on Poly(-Isopropylacrylamide), Chitosan, and Hemp-Derived Cellulose Nanocrystals.

Injectable and temperature-responsive Poly(-Isopropylacrylamide) (PNIPAAm)/Chitosan composite hydrogels reinforced with cellulose nanocrystals (CNCs) were successfully fabricated via photopolymerization. 0.1-3% (/ of cellulose nanocrystals were incorporated into the PNIPAAm/chitosan matrix to form thermo-responsive injectable composite hydrogels.