Publications by authors named "R Nandwani"
Article Synopsis
- To track global progress in reducing HIV incidence, a reliable evaluation method is essential since usual HIV diagnosis dates can misrepresent when the infection actually occurred.
- A Bayesian statistical model was developed to more accurately estimate the proportions of recent and incident HIV infections in Scotland from 2015 to 2019 by incorporating various testing results and surveillance data.
- The model found that 43.9% of diagnoses were incident infections and 21.6% were recent, particularly high among people who inject drugs, demonstrating the model's potential to enhance understanding of HIV transmission dynamics amidst data limitations.
Introduction: HIV pre-exposure prophylaxis (PrEP), in which people take HIV medication to prevent HIV acquisition, underpins global HIV transmission elimination strategies. Effective prevention needs people to adhere to PrEP and remain in care during periods of risk, but this is difficult to achieve. We undertook a process evaluation of Scotland's PrEP programme to explore barriers and facilitators to PrEP adherence and retention in care and to systematically develop evidence-based, theoretically-informed recommendations to address them.
View Article and Find Full Text PDF3D bioprinting is revolutionizing the fields of personalized and precision medicine by enabling the manufacturing of bioartificial implants that recapitulate the structural and functional characteristics of native tissues. However, the lack of quantitative and noninvasive techniques to longitudinally track the function of implants has hampered clinical applications of bioprinted scaffolds. In this study, multimaterial 3D bioprinting, engineered nanoparticles (NPs), and spectral photon-counting computed tomography (PCCT) technologies are integrated for the aim of developing a new precision medicine approach to custom-engineer scaffolds with traceability.
View Article and Find Full Text PDFBackground: HIV pre-exposure prophylaxis (PrEP) is key to HIV transmission elimination but implementation is challenging and under-researched. We undertook a process evaluation of the first 2years of a national PrEP program to explore barriers and facilitators to implementation and to develop recommendations to improve implementation, focusing on PrEP uptake and initiation.
Methods: Stage 1 involved semi-structured telephone interviews and focus groups (September 2018-July 2019) with geographically and demographically diverse patients seeking/using/declining/stopping PrEP (n =39), sexual healthcare professionals (n =54), community-based organisation service users (n =9) and staff (n =15) across Scotland.