Publications by authors named "R Nabeshima"
Thoracic descending aortic perforation with overlap syndrome (systemic sclerosis and dermatomyositis) is a rare, unreported vascular pathology. We describe the case of a 75-year-old woman who presented with chest tightness, back pain, and dyspnea. Computed tomography revealed a pinhole rupture in the descending aorta.
View Article and Find Full Text PDFA man in his 60s developed a pancreatic pseudocyst postoperatively after an open graft replacement for a ruptured abdominal aortic aneurysm. Endoscopic drainage was performed; however, this led to an aortic graft infection due to macroscopic communication with the perigraft cavity. Percutaneous drainage was performed to manage the pancreatic fistula and graft infection simultaneously.
View Article and Find Full Text PDFResponse of patients with acute respiratory failure caused by COVID-19 to awake-prone position outside the intensive care unit based on pulmonary involvement.
Clinics (Sao Paulo)
December 2021
Article Synopsis
- The study aimed to assess the effects of having COVID-19 patients with acute respiratory failure lie in a prone position while awake, outside of ICUs, as a way to improve treatment outcomes and reduce mortality.
- Conducted on 48 patients, the findings showed that 64.6% responded positively to this maneuver, and the SpO2/FiO2 index effectively predicted the need for intubation, demonstrating a sensitivity of 85% and specificity of 75%.
- Results indicate that those who responded to the prone position had significantly lower hospital mortality and shorter stays, suggesting it could be an effective early intervention for improving the condition of COVID-19 patients.
Small intestinal mononuclear cells that express CX3CR1 (CX3CR1 cells) regulate immune responses. CX3CR1 cells take up luminal antigens by protruding their dendrites into the lumen. However, it remains unclear how dendrite protrusion by CX3CR1 cells is induced in the intestine.
View Article and Find Full Text PDFArticle Synopsis
- The gene Fam60a, which is crucial for mouse embryonic development, interacts with the Sin3a-Hdac transcriptional complex and its absence leads to underdeveloped visceral organs and embryonic death.
- Fam60a plays a role in regulating gene expression by being recruited to the promoter regions of various genes, affecting their upregulation or downregulation during development.
- Additionally, Fam60a appears to influence DNA methylation patterns, particularly in mutant embryos, suggesting it is essential for proper embryogenesis through its regulatory effects on gene promoters.