Publications by authors named "R N Saab"
Introduction: Congenital pyloric web or diaphragm are rare causes of Gastric Outlet Obstruction (GOO) after infancy, representing approximately 1 % of gastrointestinal obstructions. While it typically presents in the neonatal period with nonbilious vomiting, delayed diagnosis beyond infancy is exceptionally rare.
Presentation Of The Case: An 11-year-old girl with presented with one-month history of postprandial vomiting.
Article Synopsis
- - Congenital peribronchial myofibroblastic tumor (CPMT) is a rare benign tumor found in infants, identified by unique histological features, including cartilaginous islands and spindle cells, which can lead to serious complications despite its benign classification.
- - Genetic analysis reveals that a specific alteration, the EGFR kinase domain duplication (KDD), is a common oncogenic driver in CPMT cases, suggesting that CPMT and similar tumors, like congenital mesoblastic nephromas, may share underlying molecular mechanisms and be related.
- - Following surgical resection of the tumors, patients demonstrated varied outcomes; while one patient died shortly after surgery, the remaining three were free of recurrence, indicating
Background/objectives: To evaluate the long-term outcomes of patients enrolled in the retinoblastoma programme at the Children's Cancer Institute of the American University of Beirut Medical Center (AUBMC) and to assess the effects of the Lebanese economic crisis and the COVID-19 pandemic on treatment outcomes.
Subjects/methods: A retrospective review of medical charts was conducted for retinoblastoma patients enrolled in the programme from 2012 to 2022. Parameters included age at diagnosis, gender, nationality, tumour characteristics, treatment modalities, follow-up duration, imaging results, and genetic testing outcomes.
Aggressive Pediatric Primitive Round Cell Tumors with MN1::ZNF341 Fusion: A Mimic of Neuroblastoma.
Pediatr Blood Cancer
January 2025
Neuroblastoma is one of the most common tumors in young children, arising from the adrenal medulla or paraspinal sympathetic ganglia. We describe primitive round cell tumors presenting in three patients less than 1.5 years old, with striking clinical and pathologic similarities to neuroblastoma.
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- * It found that stronger beliefs in equal childcare (both in what is considered normal and what should be the case) are associated with the availability of parental leave policies.
- * While the data suggests that changes in parental leave policies can shift perceptions of social norms over time, the study acknowledges that it cannot definitively determine cause-and-effect relationships due to its cross-sectional design.