Introduction White spot lesions (WSLs) are opacities formed due to decalcification occurring in the enamel's subsurface layer. These lesions are most commonly seen in patients during and after fixed orthodontic treatment due to undisturbed accumulation of plaque. Other factors that can predispose to WSLs are enamel hypomineralization, hypomaturation, hypoplasia, and disruption in the levels of salivary calcium, phosphate, bicarbonate, and fluoride.
View Article and Find Full Text PDFRationale: Early mortality in intracerebral hemorrhage (ICH) is due to hematoma volume (HV) expansion, and there are no effective treatments available other than reduction in blood pressure. Tranexamic acid (TXA) a hemostatic drug that is widely available and safe can be a cost-effective treatment for ICH, if proven efficacious.
Hypothesis: Administration of TXA in ICH patients when given within 4.
Unlabelled: Intestinal microbes, whether resident or transient, influence the physiology of their hosts, altering both the chemical and the physical characteristics of the gut. An example of the latter is the human pathogen ability to induce strong mechanical contractions, discovered in zebrafish. The underlying mechanism has remained unknown, but the phenomenon requires the actin crosslinking domain (ACD) of 's type VI secretion system (T6SS), a multicomponent protein syringe that pierces adjacent cells and delivers toxins.
View Article and Find Full Text PDF