Publications by authors named "R N O'Brien"

Purpose: Spectral-domain OCT angiography (SD-OCTA) scans were used in an algorithm developed for swept-source OCT angiography (SS-OCTA) scans to determine if SD-OCTA scans yielded similar results for the measurement of hyperreflective foci (HRF) in intermediate age-related macular degeneration (iAMD).

Design: Retrospective study.

Participants: Forty eyes from 35 patients with iAMD.

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Objective: This study aimed to create and validate a novel measure of gender-related minority stress in transgender and non-binary adolescents (TNBA). TNBA face higher risks of varied behavioral health concerns compared to their cisgender peers, a disparity often attributed to the presence of minority stress due to discrimination. To date, no comprehensive measures of gender-related minority stress exist for use with TNBA.

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Introduction: Episodes of alienation and/or anomie in pharmacists have been reported in historical accounts since the 19th century. Alienation and anomie are distinct types of psychological or social ills where people are problematically separated from, or their skills and values are misaligned with, others and their environment. Alienation and/or anomie can be important precursors of many negative work experiences, including job dissatisfaction, burnout and/or intention to leave.

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Article Synopsis
  • This study aimed to confirm the reliability of measuring choriocapillaris flow deficit (CCFD) within a specific macular grid and to track these measurements over time.
  • Researchers utilized advanced imaging technology to gather data, excluding certain areas in the scans to accurately calculate CCFD percentages in both normal eyes and those with eye conditions.
  • The findings showed that the methodology is effective for monitoring changes in CCFD, particularly in cases where drusen (eye abnormalities) resolved, demonstrating the practicality of the grid strategy for longitudinal studies.
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Article Synopsis
  • The study explores the development of a linac-mounted photon-counting detector (PCD) for image-guided radiotherapy (IGRT) that could significantly enhance imaging by improving soft-tissue contrast and spatial resolution compared to traditional flat panel detectors (FPDs).
  • Researchers characterized the image quality of the PCD, focusing on parameters like 2D spatial resolution, noise, and contrast, by comparing it with an FPD using various imaging techniques and calibration methods.
  • Results showed that the PCD provides a linear energy calibration and better raw contrast in images, suggesting its potential for improved tumor delineation in radiation therapy applications.
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