Republican Rules of Reproduction and "Flipping the Script" on U.S. Health Care Reform.

Given the relatively conservative and marketized nature of U.S. health care reform, it remains unclear both why Republican resistance has been so intractable through much of the Affordable Care Act's (ACA's) tenure and why it has so suddenly receded into the background.

Inflammatory Bowel Disease in Children with Elevated Serum Gamma Glutamyltransferase Levels.

Objective: To assess the characteristics of inflammatory bowel disease and disease prognosis among children with elevated gamma glutamyltransferase (GGT) and primary sclerosing cholangitis (PSC)-ulcerative colitis (UC).

Study Design: Our longitudinal, population-based cohort comprised all children and young adults diagnosed with UC in the Canadian province of Manitoba between 2011 and 2018. Diagnosis of PSC was confirmed based on a combination of cholestatic biochemical markers and cholangiographic features.

Studies towards the synthesis of medermycin via Dötz benzannulation.

The C-arylglycosides are available in enantiomerically pure form via the Dötz benzannulation reaction between Fischer alkenyl chromium carbene complexes and alkynes; it also could be converted to a precursor of medermycin by O-carbamate directed ipso bromination and nitrile substitution in good overall yields.