The effects of chronic exercise on anesthesia induced hepatotoxicity.

Unlabelled: A hypoxic rat model of halothane-induced hepatotoxicity, which is known to produce liver damage, was used to determine the effects of chronic exercise on halothane-induced hepatotoxicity and on reduced hepatic glutathione (GSH) levels. Metabolism of volatile anesthetics may generate metabolites that can cause mild and transient hepatotoxicity.

Methods: Six male Sprague-Dawley rats completed a 10-wk (5 d x wk(-1)) treadmill running protocol.

High-quality filtration allows reuse of anesthesia breathing circuits resulting in cost savings and reduced medical waste.

Study Objectives: To determine if the new Filta-Therm filter prevents contamination and allows the reuse of breathing circuit with considerable cost and environmental savings.

Design: Prospective study.

Patients: 52 ASA physical status I, II, III, and IV patients, aged 18 to 75 years.