Clinical significance of NOTCH1 and FBXW7 alterations in adult T-cell leukemia/lymphoma.

Here, we investigated the clinical significance of NOTCH1 and FBXW7 alterations for adult T-cell leukemia/lymphoma (ATLL) treatment outcomes. NOTCH1 alterations were identified in 37 (14.4%) of 257 patients, of which 33 were single nucleotide variants/insertion-deletions in the PEST domain, and 7 were in the heterodimerization or LIN-12/Notch repeats domains.

Color adjustment potential of universal shade bulk-fill resin composites.

This study investigates how the cavity depth of restorations influences the color adjustment potential of universal shade bulk-fill resin composites. Standard cavities, with diameters of 4 mm and depths of either 2 or 4 mm, were created at the center of artificial teeth occlusal surfaces. A structural-colored bulk-fill resin composite and two pigment-incorporated universal shade bulk-fill resin composites were used.

Influence of luting strategies on dentin bond performance of self-adhesive resin luting cement in combination with a universal adhesive.

Objectives: This study aimed to evaluate the dentin bond performance of various resin luting cement (RLC) systems combined with universal adhesives in different luting strategies.

Materials And Methods: Three self-adhesive resin luting cements (SRLCs) were used with universal adhesives as primers. Twelve specimens per group were prepared to measure shear bond strength (SBS) under distinct luting strategies in etch-&-rinse and self-etch modes.

Influence of in-office whitening on the color matching and surface characteristics of single-shade resin composites.

Objective: The color matching of single-shade resin composites after in-office whitening was investigated.

Materials And Methods: Four single-shade resin composites were used. A total of 35% hydrogen peroxide was used as the whitening agent.

Influence of etching mode on bonding performance of self-adhesive flowable resin composites to bovine teeth.

This study aimed to evaluate the bonding performance of self-adhesive flowable resin composites (SARs) to bovine teeth. Three SARs, one experimental, and two commercially available products, were used. The study parameters were shear bond strength (SBS), microleakage, and scanning electron microscopy (SEM) evaluation of bonding interfaces.