Publications by authors named "R Montiague"
Article Synopsis
- The study investigates how clinically relevant levels of bupivacaine and levobupivacaine affect norepinephrine release from cardiac nerves, which is crucial for heart function.
- Results showed that both anesthetics significantly reduced norepinephrine release and heart contractions, with their effects being comparable to tetrodotoxin, a known nerve blocker.
- The findings suggest that these local anesthetics can impair cardiac sympathetic transmission, which may contribute to their cardiotoxic effects in clinical settings.
Unlabelled: We compared the clinical efficacy of 1.5% lidocaine in dextrose 7.5% in water, which is currently available as a commercial preparation but approved for use only in obstetrical patients, with the traditional 5% lidocaine in dextrose 7.
View Article and Find Full Text PDFCardiac dysrhythmias are common during anesthesia and surgery. An important precipitating factor of clinically relevant arrhythmias is the introoperative use of epinephrine. Bradykinin acts as an endogenous cardioprotective substance because it suppresses ventricular dysrhythmias induced by ischemia.
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