Leveraging an Academic Practice Partnership to Support a COVID-19 Mass Vaccination Clinic.

Background: When the first coronavirus disease 2019 (COVID-19) vaccines received emergency use authorization by the U.S. Food and Drug Administration in December 2020, distribution of the vaccine began within 24 hours.

Evidence-Based Mobile Wound Application to Support Professionals in State-of-the-Art Chronic Wound Treatment.

Background: One of the most important tasks within wound management and the basis of successful wound care is a clear and accurate nursing documentation which can be created in various ways. However, this documentation is only partially standardized mainly due to the interdisciplinarity of this task.

Objectives: The goal is to overcome interdisciplinary boundaries in home care between health professionals, and to increase the patient's motivation to actively participate in wound healing by providing consistent structure and guidance.

Strategy for Deployment of Integrated Healthy Aging Regions Based Upon an Evidence-Based Regional Ecosystem-The Styria Model.

In 2013, the European Commission founded the platform European Innovation Partnership on Active and Healthy Aging as a communication and innovation network in this domain. The goal of the current study was the development of an integrated regional ecosystem for active and healthy aging for the region of Styria via a step-by-step co-creation process. A mixed model approach was used to establish an ecosystem for active and healthy aging, which includes macro-, meso- and micro-level stakeholders in the province of Styria, Austria.

Feasibility and Design of an Electronic Surgical Safety Checklist in a Teaching Hospital: A User-Based Approach.

Background: The Surgical Safety Checklist (SSC) is routinely used in operating rooms (OR) but its acceptance is low. One promising way to improve acceptance of the SSC and thus quality of patient care is digitalization.

Objective: To investigate how a digitalization of the SSC could be implemented in a teaching hospital.

A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo.

Molecular machinery involved in apoptosis plays a role in neuronal death in neurodegenerative disorders such as Parkinson's disease (PD) and Huntington's disease (HD). Several caspase inhibitors, such as the well-known peptidyl inhibitor carbobenzoxy-Val-Ala-Asp-fluoromethylketone (zVADfmk), can protect neurons from apoptotic death caused by mitochondrial toxins. However, the poor penetrability of zVADfmk into brain and toxicity limits its use therapeutically.