Publications by authors named "R Miryala"
Article Synopsis
- The study aimed to compare the effectiveness and toxicity of two radiation techniques for treating locally advanced cervical cancer: traditional 3DCRT and advanced IG-IMRT, to lessen side effects while maintaining tumor control.
- Conducted as a randomized trial, 173 patients were evaluated after being treated with external beam radiation and brachytherapy, with results showing IG-IMRT led to significantly reduced acute toxicities while maintaining similar tumor control rates to 3DCRT.
- The findings suggest that using IG-IMRT with personalized margins might be a better option for minimizing treatment-related side effects in patients with locally advanced cervical carcinoma.
Clinical reports suggest that the coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) has not only taken millions of lives, but has also created a major crisis of neurologic complications that persist even after recovery from the disease. Autopsies of patients confirm the presence of the coronaviruses in the CNS, especially in the brain. The invasion and transmission of SARS-CoV-2 in the CNS is not clearly defined, but, because the endocytic pathway has become an important target for the development of therapeutic strategies for COVID-19, it is necessary to understand endocytic processes in the CNS.
View Article and Find Full Text PDFBackground: Pyogenic spondylodiscitis (PS) is a rare infection involving the intervertebral disk space, adjacent vertebral endplates, and vertebral bodies. PS occurs in the elderly and immunocompromised patients, and is an uncommon cause of initial and/or postoperative PS. There are only seven cases involving this organism reported in literature.
View Article and Find Full Text PDFAim: To determine the iatrogenic absorbed dosage of radiation of the patient in milligray (mGy) computerised tomography dose index volume (CTDIvol) when tested with multidetector computerised tomography (MDCT) in the emergency department (ED) setting and calculate the absorbed dosage of radiation per clinically actionable result and emergently treatable finding (ETF).
Setting: The University of Texas Medical Branch (UTMB) ED located in Galveston, Texas, USA, is a level 1 trauma and tertiary referral centre treating 70,000 patients per annum.
Method: A retrospective cross-sectional data analysis of 770 emergency patients investigated by MDCT in July 2007.