Bupropion attenuates nicotine abstinence syndrome in the rat.

Rationale: Bupropion reduces discomfort and craving associated with smoking cessation. This study determined whether a rat model of nicotine dependence could detect such nicotine abstinence-alleviating effects.

Objectives: Experiments determined whether the abstinence-alleviating effects of bupropion were detectable by (1) behavioral abstinence signs precipitated by the nicotinic antagonist mecamylamine, (2) place aversion conditioned to mecamylamine-precipitated nicotine abstinence, and (3) spontaneous behavioral abstinence signs after abrupt nicotine withdrawal.

Physical and psychologic rehabilitation outcomes for pediatric patients who suffer 80% or more TBSA, 70% or more third degree burns.

Advances in medical management have dramatically decreased the mortality of children with massive burn injuries, which raises many questions about the expected quality of life for these young survivors. In this article, we address this issue by examining the functional and psychological adaptation of 41 young survivors with 88% mean total body surface area (TBSA) burns and 85% mean third degree TBSA burns. Patient scores were compared with normative data on standardized psychological measures of adjustment and on performance of age appropriate activities of daily living (ADL) skills.

Are your thoughts of facial pressure transparent?

Facial burns present many psychological and rehabilitation challenges. Many of our patients with facial burns who are children and adolescents have expressed that they prefer to wear the transparent face mask instead of the Jobst hood (Beiersdorf Jobst Inc, Charlotte, NC) with an underlying silicone face pad. However, questions have been raised about the consistency and amount of pressure provided by the transparent face mask.