Publications by authors named "R Mesman"
Terrestrial geothermal ecosystems are hostile habitats, characterized by large emissions of environmentally relevant gases such as CO , CH , H S and H . These conditions provide a niche for chemolithoautotrophic microorganisms. Methanotrophs of the phylum Verrucomicrobia, which inhabit these ecosystems, can utilize these gases and grow at pH levels below 1 and temperatures up to 65°C.
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- ANME archaea are uncultivated microorganisms that play a key role in oxidizing methane, a significant greenhouse gas.
- Researchers cultivated ANME-2d ('Ca. Methanoperedens') in bioelectrochemical systems and found that these archaea accounted for a large portion of the electrical current generated during methane oxidation.
- The study suggests the EET mechanism for methane oxidation may involve an unidentified protein complex and OmcZ nanowires, showing consistency across different electrode potentials.
The outer membrane (OM) protects Gram-negative bacteria against a hostile environment. The proteins embedded in the OM fulfil a number of tasks that are crucial to the bacterial cell. In this study, we identified and characterised a major outer membrane protein (WP_009059494) from Methylacidiphilum fumariolicum SolV.
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- The study investigates how budget allocation within hospitals can affect the financial performance of hospital care, focusing on the interaction between reimbursement and distribution models in Dutch hospitals.
- An online survey was conducted with financial senior management from 49 Dutch hospitals, achieving a 78% response rate, revealing that the most common reimbursement model is price-volume with capped prices, while incremental budgeting is the dominant internal funding method.
- Findings indicate that there is only a partial integration of contract changes into hospital budgets, suggesting that discrepancies between reimbursement and distribution models could hinder the effectiveness of financial incentives intended to improve hospital care.
Article Synopsis
- Bacterial lipoproteins, like WP_009060351, contain a lipid-modified cysteine that anchors them to cell membranes and are crucial for various physiological functions.
- Transcriptomic analysis of the methanotroph Methylacidiphilum fumariolicum SolV identified WP_009060351 as a highly expressed lipoprotein, with specific amino acid sequences indicating its unique role in methanotrophs and verrucomicrobial species.
- Experiments in Escherichia coli showed that WP_009060351 forms dimeric and tetrameric proteins, and its presence in membrane and peptidoglycan fractions suggests it may help connect the outer membrane to the peptidoglycan layer.