Publications by authors named "R McDermott"
Article Synopsis
- Neoadjuvant radiotherapy is crucial for treating locally advanced rectal cancer, and this study compares the quality-of-life outcomes between two techniques: three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT).
- A phase II randomized trial involved 94 patients who received chemoradiotherapy and were assigned to either 3DCRT or IMRT; their quality of life was assessed using specific questionnaires throughout the treatment and at a six-month follow-up.
- Although the trial ended early due to the futility of its primary endpoint, the results indicated that while emotional functioning improved, other aspects of quality of life declined; notably, IMRT showed better physical and role functioning during the final week
Purpose: To describe the Irish Prostate Cancer Outcomes Research (IPCOR) registry. The cohort was collected to inform and improve the prostate cancer journey of men in Ireland.
Participants: Established in 2015, IPCOR was a unique large-scale prospective cohort study registering men with prostate cancer in Ireland.
Commercial activity has positive and negative effects on health. Adverse commercial impacts on health are underpinned by corporate power and economic models and policy that prioritize economic growth, rather than a wellbeing economy that prioritizes health, equity and sustainability. Health in all policies (HiAP) aims to ensure that all policies promote health and health equity, using processes including health impact assessment (HIA).
View Article and Find Full Text PDFIntroduction: The Irish Prostate Cancer Outcomes Research (IPCOR) Study collected longitudinal data on men newly diagnosed with Prostate Cancer (PC). Understanding the nuances of disease presentation is essential, considering the high incidence of PC in Ireland. This study aims to characterise disease presentation features, identify factors related to socio demographic disparities in presentation following opportunistic screening, and shed light on potential inequality challenges within Ireland's healthcare structure.
View Article and Find Full Text PDFSeveral life-prolonging therapies with diverse mechanisms of action (MoA) are available for the treatment of metastatic hormone-sensitive/castration-resistant prostate cancer, with many patients requiring multiple lines of therapy. Nevertheless, treatment optimization to further delay disease progression and improve overall survival remains an unmet need. Despite the number of agents with differing MoAs approved for advanced prostate cancer, many patients receive only one or two life-prolonging therapies.
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