Using microfluidic shear to assess transfusion requirements in trauma patients.

Background: Viscoelastic assays have widely been used for evaluating coagulopathies but lack the addition of shear stress important to clot formation. Stasys technology subjects whole blood to shear forces over factor-coated surfaces. Microclot formation is analyzed to determine clot area (CA) and platelet contractile forces (PCFs).

RPGR: Deep Phenotyping and Genetic Characterization With Findings Specific to the 3'-end of ORF15.

Purpose: To describe a group of patients with retinitis pigmentosa GTPase regulator (RPGR)-related retinopathy with a tapetal-like retinal sheen and corresponding changes in the reflectivity of the ellipsoid zone on optical coherence tomography (OCT) imaging.

Methods: A retrospective case series of 66 patients with a disease-causing variant in RPGR was performed. An expert examiner, masked to patient demographics, clinical evaluations, and specific RPGR variant, analyzed color fundus photographs for the presence of a tapetal-like retinal sheen and assessed OCT images for the presence of an abnormally broad hyper-reflective band in the outer retina.

Tunable zero-energy Dirac and Luttinger nodes in a two-dimensional topological superconductor.

Cooper pairing in ultrathin films of topological insulators, induced intrinsically or by proximity effect, can produce an energetically favorable spin-triplet superconducting state. The spin-orbit coupling acts as an SU(2) gauge field and stimulates the formation of a spin-current vortex lattice in this superconducting state. Here we study the Bogoliubov quasiparticles in such a state and find that the quasiparticle spectrum consists of a number of Dirac nodes pinned to zero energy by the particle-hole symmetry.

Relation of non-exercise walking activity with exercise performance in patients with peripheral artery disease: NEW activity for PAD.

Introduction: Community-based structured exercise training (CB-SET) programs are beneficial for patients with peripheral artery disease (PAD). However, the impact of lower levels of walking activity accumulated separately from formal exercise is unclear. The aim of this study was to determine the relation of non-exercise walking (NEW) activity with exercise performance in PAD.

Mechanical adaptations in walking using carbon fiber ankle foot orthoses for patients with peripheral artery disease.

Background: The effectiveness of community-based walking programs for patients with peripheral artery disease (PAD) can be limited by calf claudication during exercise. Recent evidence finds adding carbon fiber ankle foot orthoses (AFO) to a walking program can result in improvements in patient mobility and delay claudication onset when walking.

Research Question: How may carbon fiber AFO alter ankle walking mechanics and corresponding triceps surae muscle recruitment in a manner that could improve patient mobility?

Methods: In this repeated measures cohort study, fifteen patients with PAD were fit with bilateral AFO before completing self-paced gait analysis including electromyography.