A Covariant Non-Local Model of Bohm's Quantum Potential.

Assuming that the energy of a gas depends non-locally on the logarithm of its mass density, the body force in the resulting equation of motion consists of the sum of density gradient terms. Truncating this series after the second term, Bohm's quantum potential and the Madelung equation are obtained, showing explicitly that some of the hypotheses that led to the formulation of quantum mechanics do admit a classical interpretation based on non-locality. Here, we generalize this approach imposing a finite speed of propagation of any perturbation, thus determining a covariant formulation of the Madelung equation.

Mixing Improvement in a T-Shaped Micro-Junction through Small Rectangular Cavities.

The T-shaped micro-junction is among the most used geometry in microfluidic applications, and many design modifications of the channel walls have been proposed to enhance mixing. In this work, we investigate through numerical simulations the introduction of one pair of small rectangular cavities in the lateral walls of the mixing channel just downstream of the confluence region. The aim is to preserve the simple geometry that has contributed to spread the practical use of the T-shaped micro-junction while suggesting a modification that should, in principle, work jointly with the vortical structures present in the mixing channel, further enhancing their efficiency in mixing without significant additional pressure drops.

Dysphagic disorder in a cohort of COVID-19 patients: Evaluation and evolution.

Background: COVID-19 is a multisystem disease complicated by respiratory failure requiring sustanined mechanical ventilation (MV). Prolongued oro-tracheal intubation is associated to an increased risk of dysphagia and bronchial aspiration. Purpose of this study was to investigate swallowing disorders in critically ill COVID-19 patients.

Hemoadsorption Treatment with CytoSorb® in Probable Hemophagocytic Lymphohistiocytosis: A Role as Adjunctive Therapy?

Acute hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disease, with an annual incidence of 1 : 800,000 people. The disease is characterized by a cytokine storm, with concomitant macrophage and natural killer (NK) cell activation; death can occur from multiple organ failure or complications such as bleeding diathesis. Therefore, HLH treatment remains a challenging one.

Low PEEP Mechanical Ventilation and PaO/FiO Ratio Evolution in COVID-19 Patients.

Invasive mechanical ventilation (IMV) is the standard treatment in critically ill COVID-19 patients with acute severe respiratory distress syndrome (ARDS). When IMV setting is extremely aggressive, especially through the application of high positive-end-expiratory respiration (PEEP) values, lung damage can occur. Until today, in COVID-19 patients, two types of ARDS were identified (L- and H-type); for the L-type, a was supposed to be preferred, but data are still missing.