Publications by authors named "R Massari"
Purpose: Sentinel lymph node biopsy (SLNB) has been recognized as "the gold standard" for axillary staging in early breast cancer patients with clinically negative lymph nodes, resulting in significant morbidity decrease and quality of life improvement. This study aims to validate the performance of a newly developed handheld portable gamma camera (PGC) produced by Imagensys (Italy), in detecting and locating sentinel lymph nodes (SLNs) during the preoperative and intraoperative phases in breast cancer patients compared to conventional lymphoscintigraphy.
Methods: Adult female patients with histologically confirmed breast cancer, candidates for surgery and SLNB, were prospectively enrolled in this open-label, pre-marketing clinical trial.
Article Synopsis
- The oviduct is super important for reproduction, helping with fertilization and where embryos start to develop.
- Researchers used special technology called MicroCT to carefully study two parts of the oviduct, finding differences in their shapes and sizes.
- The study showed that these structural differences might affect how the oviduct works, and it could help create a mini version of it for research.
Article Synopsis
- Many brain tumors in kids are hard to treat, but new therapies might help them!
- A study with mice showed that a chemical called Cxcl3 can help brain cells move and develop properly, reducing the size of tumors!
- Researchers also found that Cxcl3 works in different types of brain tumors in humans, suggesting it could be a useful treatment option!
Unlabelled: Tumor associated fibroblasts (TAFs) play a key role in tumor growth and metastatization. TAFs overexpress different biomarkers that are usually expressed at low levels in physiological conditions. Among them are the fibroblast growth factor receptors (FGFRs) that bind the fibroblast growth factors (FGFs).
View Article and Find Full Text PDFRecently, we described synthetic sulfolipids named Sulfavants as a novel class of molecular adjuvants based on the sulfoquinovosyl-diacylglycerol skeleton. The members of this family, Sulfavant A (), Sulfavant R (), and Sulfavant S (), showed important effects on triggering receptor expressed on myeloid cells 2 (TREM2)-induced differentiation and maturation of human dendritic cells (hDC), through a novel cell mechanism underlying the regulation of the immune response. As these molecules are involved in biological TREM2-mediated processes crucial for cell survival, here, we report the synthesis and application of a fluorescent analogue of Sulfavant A bearing the 4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza--indacene moiety (Me-BODIPY).
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