Publications by authors named "R Marzio"
Background: The PERMA Model, as a positive psychology conceptual framework, has increased our understanding of the role of Positive emotion, Engagement, Relationships, Meaning, and Achievements in enhancing human potentials, performance and wellbeing. We aimed to assess the utility of PERMA as a multidimensional model of positive psychology in reducing physician burnout and improving their well-being.
Methods: Eligible studies include peer-reviewed English language studies of randomized control trials and non-randomized design.
Effective clinical treatments for volumetric muscle loss resulting from traumatic injury or resection of a large amount of muscle mass are not available to date. Tissue engineering may represent an alternative treatment approach. Decellularization of tissues and whole organs is a recently introduced platform technology for creating scaffolding materials for tissue engineering and regenerative medicine.
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- The study used the CAP-Trapper method to create human full-length-enriched cDNA libraries, leading to the identification of 342 potential new human genes.
- About 23,000 clones from various tissues and developmental stages were sequenced, revealing 5,300 unique cDNAs, with 40% extending previously known gene annotations and 662 being splice variants.
- Gene expression analysis indicated that 260 out of the 342 unknown clones were expressed in various cell lines or tissues, suggesting they could be novel genes, although only a small number are likely to code for proteins.
LNCIB has been producing a variety of human full-length-enriched, normalized and subtracted cDNA libraries from various cell lines and tissues in different developmental stages by using the CAP-Trapper method. By sequencing 23000 clones of these libraries we identified a pool of about 5800 good quality unique cDNAs. After BLAST analysis on Human RefSeq/Unigene databases, 1717 of these sequences remained with no or poor annotation.
View Article and Find Full Text PDFCD69, also known as activation inducer molecule, very early activation antigen, MLR-3 and Leu-23, is a member of the natural killer (NK) cell gene complex family of signal transducing receptors. CD69 is as a type II transmembrane glycoprotein with a C-type lectin binding domain in the extracellular portion of the molecule. CD69 expression is induced in vitro on cells of most hematopoietic lineages, including T and B lymphocytes, NK cells, murine macrophages, neutrophils and eosinophils, while it is constitutively expressed on human monocytes, platelets and epidermal Langerhans cells.
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