Antioxidant Valorization of PLE Extracts from Macroalgae (): In Vitro Assessment of Nanoemulsions Against Oxidative Stress.

Driven by a growing global interest in natural products, macroalgae have emerged as a prime source for nutraceuticals and pharmaceutical applications. In the current research, the effect of oven-drying (OD) and freeze-drying (FD), as well as the pressurized liquid extraction (PLE) conditions, were investigated in relation to the polyphenols, flavonoids, carotenoids, chlorophylls, and tocochromanols levels in extracts. The ethanol-water extracts (1:1) obtained with PLE-150 °C from macroalgae oven-dried (OD)-80 °C displayed the highest total polyphenol content (TPC) and total flavonoid contents (TFCs), reaching 29.

Integration of distinct cortical inputs to primary and higher order inhibitory cells of the thalamus.

The neocortex controls its own sensory input in part through top-down inhibitory mechanisms. Descending corticothalamic projections drive GABAergic neurons of the thalamic reticular nucleus (TRN), which govern thalamocortical cell activity via inhibition. Neurons in sensory TRN are organized into primary and higher order (HO) subpopulations, with separate intrathalamic connections and distinct genetic and functional properties.

The Indigenous Probiotic PH3-05 Enhances the Growth, Digestive Physiology, and Gut Microbiota of the Tropical Gar () Larvae.

Probiotics in aquaculture hold promise for enhancing fish health and growth. Due to their increased specificity and affinity for their host, indigenous probiotics may offer isolated and potentially amplified benefits. This study investigated the effects of PH3-05, previously isolated from adults of tropical gar (), on the growth, survival, digestive enzyme activity, intestinal morphology, expression of barrier and immune genes, and intestinal microbiota composition in the larvae of tropical gar.

[Role of diet in the prevention and development of Crohn's Disease].

Crohn's disease (CD) is a chronic recurrent inflammatory bowel disease (IBD) with frequent ileocolic location, although it can affect the entire gastrointestinal tract. It is characterized by the development of skipped lesions and transmural inflammation and its incidence is increasing. The etiology and pathogenesis are related to genetic susceptibility, intestinal microbiota, dysbiosis, immunological abnormalities and environmental factors (tobacco use, NSAIDs, oral contraceptives and diet).