Publications by authors named "R Martin Del Rio"

Aims: Heart failure (HF) is an emerging epidemic worldwide. Despite advances in treatment, the morbidity and mortality rate of HF remain high, and the global prevalence continues to rise. Common clinical features of HF include cardiac sympathoexcitation, disordered breathing, and kidney dysfunction; kidney dysfunction strongly contributes to sodium retention and fluid overload, leading to poor outcomes of HF patients.

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Chronic intermittent hypoxia (CIH), the main feature of obstructive sleep apnea, heightened chemosensory discharges of the carotid body (CB), which contributes to potentiate the ventilatory hypoxic response and elicits hypertension. We aimed to determine: 1) whether the persistence of cardiorespiratory alterations found in long-term CIH depend on the inputs from the CB and, 2) in what extension the activation of glial cells and neuroinflammation in the caudal region of the nucleus of the Solitary Tract (NTS) requires functional CB chemosensory activity. To evaluate these hypotheses, we exposed male mice to CIH for 60 days.

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Background: By 2030, projections indicate that nearly half of USS adults will be obese, with 29 states exceeding a 50% obesity rate. High Body Mass Index (BMI) presents particular challenges in treating diverticulitis, including worsened symptoms and increased risk of surgical complications. The Robotic Natural orifice Intracorporeal Anastomosis with Transrectal Extraction (NICE) procedure has been developed for colorectal surgeries to tackle these challenges.

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Article Synopsis
  • The study focuses on the adaptability of stone pine, a key Mediterranean species known for its high-quality pine nuts, in response to varying climatic conditions in both native and non-native environments.
  • By comparing growth patterns in southern Spain and central-southern Chile, the research examines how factors like rainfall and temperature influence stone pine's growth, particularly during drought periods.
  • Findings indicate that while exotic plantations are less sensitive to climate changes, understanding stone pine's growth responses can help inform sustainable management strategies in the face of climate change.
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Background: Very low calorie diets (VLCDs) are an obesity treatment option in the general population, but their efficacy and safety in patients on haemodialysis (HD) is unknown.

Methods: Prospective single arm study of VLCD in haemodialysis patients. All participants received 2.

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