Publications by authors named "R Marsden"

Vertebrates sniff to control the odor samples that enter their nose. These samples can not only help identify odorous objects, but also locations and events. However, there is no receptor for place or time.

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An organometallic erbium bismuth cluster complex, [K(THF)][Cp*ErBi] (), featuring a heterometallocubane core was isolated. The cube emerges from the rare Bi Zintl ion, bridging two erbium centers for the first time. SQUID magnetometry and calculations uncovered dominant antiferromagnetic coupling enabled through the chair-like hexabismuth anion.

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Article Synopsis
  • Immunogenicity testing helps understand the immune response to protein therapies, and neutralizing antibody (NAb) assays are key to characterizing anti-drug antibody responses.
  • A group of NAb assay experts has created standardized reporting recommendations to streamline communication and facilitate regulatory submissions.
  • The document outlines essential components for NAb sample analysis reports, though it does not cover the interpretation of immunogenicity data related to safety and efficacy.
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Multiple sources of evidence suggest that changes in metabolism may precede the onset of motor symptoms in amyotrophic lateral sclerosis. This study aimed to seek evidence for alterations in the levels of blood indices collected routinely in the primary care setting prior to the onset of motor symptoms in amyotrophic lateral sclerosis. Premorbid data, measured as part of routine health screening, for total cholesterol, high-density and low-density lipoprotein cholesterol, triglyceride, glycated haemoglobin A1c and creatinine were collected retrospectively from (i) a cohort of amyotrophic lateral sclerosis patients attending a specialist clinic ( = 143) and (ii) from primary care-linked data within UK Biobank.

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