Publications by authors named "R Marcos-Gragera"

Background: Multiple myeloma (MM) is an important haematological malignancy in older adults, with a relatively poor prognosis. We aimed to present the current global patterns of incidence and mortality from MM, and predict new cases and deaths by 2045.

Methods: Estimated numbers of MM cases and deaths and age-standardized (World) incidence and mortality rates per 100,000 people were obtained from the GLOBOCAN 2022 database covering 185 countries.

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In 2022, leukemia ranked as the second most common hematological malignancy after non-Hodgkin lymphoma worldwide. However, updated global estimates of leukemia incidence by subtype are unavailable. We estimated leukemia incidences for different leukemia subtypes by country, world region, and human developmental index using data from the Cancer Incidence in Five Continents databases combined with the GLOBOCAN 2022 estimates of leukemia in 185 countries.

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Background: Lung cancer (LC) is Europe's primary cause of cancer-related mortality largely due to its historically low survival rates. The aim of this study was to analyze 26-year survival trends in the province of Girona, Spain, and to identify key prognostic factors.

Methods: Population-based study of LC cases collected between 1994 and 2019, with follow-up until December 31, 2021.

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Background: 10% of postmenopausal breast cancer cases are attributed to a high body mass index (BMI). BMI underestimates body fat, particularly in older women, and therefore the cancer burden attributable to obesity may be even higher. However, this is not clear.

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Article Synopsis
  • A new modeling approach was developed to better estimate the cancer cure fraction (CF) and net survival by considering patients' increased risk of dying from causes other than cancer, rather than assuming equal mortality rates with the general population.
  • Data from EUROCARE-6 on head and neck, colorectal, and breast cancer patients aged 40-79 was analyzed, revealing a significant increase in CF, particularly among younger males with head and neck cancer who had a fourfold increased risk of dying from other causes.
  • Ignoring the higher mortality risk from non-cancer causes leads to an underestimation of the CF, which is crucial for understanding patient survival and improving their quality of life.
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