Publications by authors named "R Manny"
Validating Rules for Defining No Improvement of Visual Acuity in Childhood Amblyopia.
Invest Ophthalmol Vis Sci
January 2025
Article Synopsis
- The study emphasizes the importance of identifying when visual acuity (VA) in amblyopia patients has stabilized to inform treatment choices.
- The researchers simulated various VA measurements to assess the accuracy (false-positive and false-negative rates) of different rules for determining VA stability across multiple visits and treatments.
- Results showed significant variability in false-positive and false-negative rates depending on the measurement rules used, suggesting that clinicians should choose rules based on whether they want to minimize overlooking stabilization or misclassifying improvement.
Article Synopsis
- The study investigated factors linked to myopia progression and axial elongation in children with myopia.
- It analyzed data from a trial comparing atropine treatment with a placebo, focusing on children aged 5 to <13 with specific refractive errors and other characteristics.
- Results showed that younger children and those with higher initial myopia experienced more significant changes in refractive error and axial length, highlighting the need for treatments to slow progression in this at-risk group.
Significance: Clinicians and researchers would benefit from being able to predict the onset of myopia for an individual child. This report provides a model for calculating the probability of myopia onset, year-by-year and cumulatively, based on results from the largest, most ethnically diverse study of myopia onset in the United States.
Purpose: This study aimed to model the probability of the onset of myopia in previously nonmyopic school-aged children.
Importance: Controlling myopia progression is of interest worldwide. Low-dose atropine eye drops have slowed progression in children in East Asia.
Objective: To compare atropine, 0.
Purpose: Refractions based on the optimisation of single-value wavefront-derived metrics may help determine appropriate corrections for individuals with Down syndrome where clinical techniques fall short. This study compared dioptric differences between refractions obtained using standard clinical techniques and two metric-optimised methods: visual Strehl ratio (VSX) and pupil fraction tessellated (PFSt), and investigated characteristics that may contribute to the differences between refraction types.
Methods: Thirty adults with Down syndrome (age = 29 ± 10 years) participated.