[Diastolic Dysfunction in CKD: Cause or Effect?s].

Left Ventricular Diastolic Dysfunction (LVDD) describes changes in the heart's structure and function, leading to impaired ventricular relaxation and increased filling pressures during the diastolic phase of the cardiac cycle. In the context of isolated LVDD, the left ventricular end-diastolic volume, global contractility, and ejection fraction (EF) are normal, with EF being 50% or higher. However, as filling pressures progressively increase, diastolic dysfunction worsens.

Prevalence and clinical impact of high platelet reactivity in patients with chronic kidney disease treated with percutaneous coronary intervention: An updated systematic review and meta-analysis.

Background: High platelet reactivity (HPR) on clopidogrel and chronic kidney disease (CKD) are recognized as potent risk factors for adverse outcomes in patients suffering coronary artery disease (CAD) and undergoing percutaneous coronary intervention (PCI). However, conclusive evidence regarding their reciprocal interaction and the consequent impact on clinical events is still lacking.

Objectives: We performed a metaanalysis with the aim to evaluate the prevalence of HPR in patients with and without CKD and the incidence of major adverse cardiovascular events (MACE) according to the renal and platelet function status in current literature (co-primary endpoints).

Impact of Chronic Kidney Disease and Platelet Reactivity on Clinical Outcomes Following Percutaneous Coronary Intervention.

We investigated the interaction between chronic kidney disease (CKD) and high platelet reactivity (HPR) in determining long-term clinical outcomes following elective PCI for stable coronary artery disease (CAD). A total of 500 patients treated with aspirin and clopidogrel were divided based on the presence of CKD (defined as glomerular filtration rate of < 60 ml/min/1.73 m) and HPR (defined as a P2Y12 reaction unit value ≥ 240 at VerifyNow assay).

Second order root control of self-ligating brackets and traditional brackets: a "typodont" study.

Aim: Aim of the study was to evaluate if self-ligating brackets (SLB) and conventional brackets (CB) have the same degree of second order root control in closing extraction spaces.

Methods: Two resin models, left and right sides of an upper arch, with two wells in the premolar area, were used. Wells have been filled with wax and resin premolars with anatomic root structure were placed in them.

Traditional plaster casts and dental digital models: intra-examiner reliability of measurements.

Unlabelled: The aim of this study was to compare the intra-examiner reliability of measurements made on plaster cast and dental digital models.

Material And Methods: Five young patients with different occlusal patterns were selected and their dental casts and corresponding digital models were obtained. Twenty expert orthodontists were asked to measure two times both the traditional and digital models.