Publications by authors named "R Manavaki"
Radiomics analysis of [F]-fluorodeoxyglucose ([F]-FDG) PET images could be leveraged for personalised cancer medicine. However, the inherent sensitivity of radiomic features to intensity discretisation and voxel interpolation complicates its clinical translation. In this work, we evaluated the robustness of tumour [F]-FDG-PET radiomic features to 174 different variations in intensity resolution or voxel size, and determined whether implementing parameter range conditions or dependency corrections could improve their robustness.
View Article and Find Full Text PDFBackground: To study the reproducibility of Na magnetic resonance imaging (MRI) measurements from breast tissue in healthy volunteers.
Methods: Using a dual-tuned bilateral Na/H breast coil at 3-T MRI, high-resolution Na MRI three-dimensional cones sequences were used to quantify total sodium concentration (TSC) and fluid-attenuated sodium concentration (FASC). B-corrected TSC and FASC maps were created.
Article Synopsis
- This study investigates the link between hypoxia and vascular function in estrogen receptor-positive breast cancer using advanced imaging techniques and immunohistochemical markers.
- The research involved treatment-naive women who underwent [F]-FMISO-PET/MRI, measuring variables like vessel diameter and microvessel density to assess hypoxia.
- Results showed a negative correlation between hypoxia and vascular metrics, indicating that lower blood vessel density and smaller vessel sizes are linked to increased hypoxia in breast tumors.
Background: Assessing inflammatory disease activity in large vessel vasculitis (LVV) can be challenging by conventional measures.
Objectives: We aimed to investigate somatostatin receptor 2 (SST) as a novel inflammation-specific molecular imaging target in LVV.
Methods: In a prospective, observational cohort study, in vivo arterial SST expression was assessed by positron emission tomography/magnetic resonance imaging (PET/MRI) using Ga-DOTATATE and F-FET-βAG-TOCA.