Publications by authors named "R Makary"
Malignant phyllodes tumors (MPTs) represent the most pernicious type of intralobular stromal proliferation known as a "fibroepithelial lesion" (FEL). They comprise a small fraction of breast malignancies and can present as either a pure MPT or sometimes include a heterologous component (liposarcoma, chondrosarcoma, osteosarcoma, or rhabdomyosarcoma). Of the fraction of MPTs that include heterologous components, very little about those with chondroblastic osteosarcomatous differentiation has been described in the literature.
View Article and Find Full Text PDFBenign cystic mesothelioma (BCM), also known as peritoneal inclusion cyst, is a benign mesothelial lined cystic lesion, nearly always described in the pelvis of adult females. The hepatic location of BCM is rarely reported in the literature. We report a case of hepatic benign cysts in a 65-year-old woman that was incidentally discovered by imaging studies 12 years ago as a small cyst.
View Article and Find Full Text PDFArticle Synopsis
- - PTLD, a rare but serious complication affecting about 5% of transplant patients, can be particularly difficult to diagnose when it presents as isolated central nervous system (CNS) lesions, as symptoms often mimic other conditions.
- - This case study discusses a 72-year-old woman who developed severe headaches and confusion 11 years post-kidney transplant, leading to imaging that revealed abnormal brain swelling, which required surgery for further investigation.
- - The diagnosis was confirmed as polymorphic type PTLD, highlighting the importance of monitoring immunosuppressive treatments and the need for prompt diagnosis to improve survival chances for affected patients.
Dedifferentiated chondrosarcoma (DDCS) is a rare entity, constituting only 1-2% of all primary bone tumors, and has a dismal prognosis. Nearly two-thirds of the primary tumors of DDCSs are found in the appendicular skeleton, mostly involving the femur, humerus, and pelvis. DDCS of the small bones of the hand and foot are exceedingly rare with only four cases documented in the literature so far.
View Article and Find Full Text PDFArticle Synopsis
- * Complete surgical removal is difficult due to the tumor's invasive nature, often resulting in recurrence; hence, treatments typically include surgery, radiation therapies like Gamma knife, and ongoing hormone management.
- * Recent advances in surgical techniques and radiation therapies, along with exploration of novel chemotherapy and immunotherapy options, are evolving the management strategies for CPs, improving outcomes while minimizing complications.