New Behavior Records of the Oxysternon palemo Castelnau, 1840 (Coleoptera: Scarabaeidae: Scarabaeinae) in Cerrado.

The present study reports new behavioral records for Oxysternon palemo Castelnau, 1840 in Cerrado. According to its nesting habits and resource allocation, this species of dung beetle is traditionally classified as coprophagous and paracoprid, transporting portions of dung through tunnels excavated below the resource. We observed a male individual moving a pequi seed (Caryocar brasiliensis Cambess.

DLK1 Is Associated with Stemness Phenotype in Medullary Thyroid Carcinoma Cell Lines.

Medullary thyroid carcinoma (MTC) is a rare and aggressive tumor, often requiring systemic treatment in advanced or metastatic stages, where drug resistance presents a significant challenge. Given the role of cancer stem cells (CSCs) in cancer recurrence and drug resistance, we aimed to identify CSC subpopulations within two MTC cell lines harboring pathogenic variants in the two most common MEN2-associated codons. We analyzed 15 stemness-associated markers, along with well-established thyroid stem cell markers (CD133, CD44, and ALDH1), a novel candidate (DLK1), and multidrug resistance proteins (MRP1 and MRP3).

Intake, digestibility, and behavior of horses fed açaí kernel (Euterpe oleracea Mart.) as a substitute of Mombaça grass (Megathyrsus maximus).

In this study, we analyzed the effects of including açaí kernel, in the experimental diets fed to horses on the intake and digestibility of their nutrient and the resultant effects on the behavior of horses. The experiments were conducted in Federal Rural University of Amazonia. Five mares with no defined breeds, were allocated to five treatments (the replacement of Mombaça grass (Megathyrsus maximus) with crushed açaí kernel at 0, 18.

Validation of the Portuguese MDS-UPDRS: Challenges to Obtain a Scale Applicable to Different Linguistic Cultures.

Background: The MDS-UPDRS has been available in English since 2008, showing satisfactory clinimetric results and being proposed as the new official benchmark scale for Parkinson's disease (PD), being cited as a core instrument for PD in the National Institutes of Neurological Disorders and Stroke Common Data Elements program. For this reason, the MDS created guidelines for development of MDS-UPDRS official, clinimetrically validated translations.

Objective: This study presents the formal process used to obtain the officially approved Portuguese version of the MDS-UPDRS.

SIGEPS: A System for Managing the Health Internship Program.

The healthcare sector's demand for a skilled workforce necessitates effective management of internship and residency programs. This study introduces the System for Managing the Health Internship Program (SIGEPS), aimed at addressing internship and residency management challenges in Joinville's municipal health network. The method of this study focused on developing a computational solution with applied and exploratory objectives.