Interactions between lncRNAs and cyclins/CDKs complexes; key players in determining cancer cell response to CDKs inhibitors.

Transcription takes place over a significant portion of the human genome. However, only a small portion of the transcriptome, roughly 1.2%, consists of RNAs translated into proteins; the majority of transcripts, on the other hand, comprise a variety of RNA families with varying sizes and functions.

Correlation of Two-Minute and Six-Minute Walk Tests With Spirometric Indices in Patients With Severe Chronic Obstructive Pulmonary Disease at a Selected Tertiary Care Hospital in Puducherry.

Background Chronic obstructive pulmonary disease (COPD) is a progressive respiratory condition characterised by airflow limitation and reduced exercise capacity. The Six-Minute Walk Test (6MWT) and Two-Minute Walk Test (2MWT) are commonly used to assess functional exercise capacity in COPD patients. This study aims to evaluate the correlation between the distance covered in the 2MWT and 6MWT with spirometric indices (such as Forced Expiratory Volume in 1 second (FEV₁), Forced Vital Capacity (FVC), and FEV₁/FVC) in COPD patients.

Exploring Acupuncture as an Adjunctive Therapy for Puberty Menorrhagia: A Case Report.

Background: Puberty menorrhagia, characterized by prolonged and excessive menstrual bleeding between menarche and 19 years of age, presents clinical challenges at adolescents and it is attributed to an immature hypothalamo-pituitary-ovarian axis, leading to sustained high estrogen levels and anovulation. This case report explores the efficacy of acupuncture as an adjunctive therapy for pubertal menorrhagia of a 16-year-old female with a history of irregular menstrual cycles and excessive bleeding for 41 days.

Methodology: Based on Traditional Chinese Medicine (TCM) tongue and pulse diagnostics of the patient, acupuncture needling at SP4 (Gongsun), PC 6 (Neiguan), KI 14 (Siman), SP 10 (Xuehai), LR 1 (Dadun), CV 6 (Qihai) was given once in a day for a month, each session lasting 20 min targeting to alleviate Liver blood stasis.

Enhancing AppAuthentix recommender systems using advanced machine learning techniques to identify genuine and counterfeit android applications.

Smartphone app expansion needs strict security measures to avoid fraud and danger. This study overcomes this issue by identifying apps differently. This new solution uses convolutional neural network (CNN), natural language processing (NLP), and the strong AppAuthentix Recommender algorithm to secure app stores and boost customer confidence in the digital marketplace.

Comparative Analytical Study of Intravitreal Triamcinolone Acetonide Versus Bevacizumab in Managing Diabetic Macular Edema: Insights From a Tertiary Eye Care Facility in India.

Aim: This study aims to compare the effects of intravitreal triamcinolone acetonide (IVTA) and bevacizumab (IVB) in diabetic macular edema (DME) management.

Methodology: A prospective interventional study was conducted at a tertiary eye care hospital in Tamil Nadu, India. The study received approval from the institutional ethics committee, and informed consent was obtained from all participants.