Publications by authors named "R M el Bejjani"
Article Synopsis
- This study explores the relationships between OCT biomarkers and contrast sensitivity in eyes diagnosed with intermediate age-related macular degeneration (iAMD), aiming to improve understanding of disease progression.
- A total of 205 eyes from 134 patients were analyzed; findings reveal that higher retinal pigment epithelium volume and intraretinal hyperreflective foci correlate with poorer contrast sensitivity measures.
- Over a follow-up period, approximately 43% of eyes progressed to late-stage AMD, indicating the potential clinical significance of the identified biomarkers in predicting progression.
Messenger RNA (mRNA)-based therapies are a promising approach to medical treatment. Except for infectious diseases, no other disease has mRNA-based therapies available. The eye is an ideal model for mRNA therapeutic development because it requires limited dosing.
View Article and Find Full Text PDFPurpose: To characterize a large modern cohort of patients with central retinal artery occlusion (CRAO) by describing presenting features and outcomes relating to manually segmented optical coherence tomography (OCT) features, angiographic reperfusion, and visual recovery.
Design: Retrospective clinical cohort study.
Methods: Patients with CRAO (ICD-10: H34.
Purpose: To investigate the effects of faricimab, a bispecific antibody targeting VEGF and Ang-2 (thus increasing Tie-2 activity), in patients with CSC based on a recent genetic study that implicated Tie-2 signaling in CSC pathophysiology.
Design: A retrospective interventional multicenter case series.
Methods: We included patients with chronic CSC (persistent or recurrent SRF for ≥6 months) who received at least one faricimab 6 mg injection between January 1 2022, and April 1 2024,.
Objectives: Cognitive impairment, pain and depressive symptoms are common and interrelated factors in older adults. However, the directionality and specificity of their association remains unclarified. This study explored whether these factors prospectively increase reciprocal risk and examined the longitudinal association between these factors and quality of life (QoL).
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