Publications by authors named "R M Ruff"

Background/objectives: School-based caries prevention can increase access to critical dental services and reduce oral health inequities. However, little is known regarding the incidence of dental caries in children participating in school caries prevention, and caries diagnosis is often interval censored.

Methods: In this paper, we used data from a longitudinal, school-based, randomized clinical trial of minimally invasive treatments for dental caries to estimate the per-visit incidence rate and compare the hazard of dental caries in children receiving either silver diamine fluoride or glass ionomer dental sealants.

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Several mouse lines with congenital growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis disruption have shown improved health and extended lifespan. The current study investigated how inactivating this axis, specifically during aging, impacts the healthspan. We used a tamoxifen-inducible global GH receptor (GHR) knockout mouse model starting at 12 months and followed the mice until 24 months of age (iGHRKO mice).

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Article Synopsis
  • Teledentistry is a virtual approach for dental examinations aimed at improving access to care, specifically for emergency scenarios in military settings.
  • One hundred subjects underwent both virtual and in-person dental examinations on the same day to assess the reliability of diagnoses made through these two methods.
  • Results indicated substantial agreement between virtual and in-person diagnoses, suggesting that teledentistry is an effective tool for emergency dental care.
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Background: Dental caries is the world's most prevalent noncommunicable disease, disproportionately affecting children from low-income families and rural geographic areas.

Methods: The CariedAway 3.0 study was a cluster-randomized pragmatic non-inferiority trial comparing silver diamine fluoride (SDF) to sealants and atraumatic restorations (ART) for the prevention and control of dental caries.

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