Publications by authors named "R M Mukhtar"
Background: This study investigates the relationship between the recurrence of Chronic Otitis Media with Otorrhea (ChOLE) and patient-related factors, surgical procedures, and elements. It involved 190 patients and aimed to identify significant relationships between demographics, condition severity, surgical approaches, comorbidities, problem classification, hygiene practices, and education level. Statistical analyses, including Chi-Square tests, were used to determine these connections.
View Article and Find Full Text PDFBackground: This multicenter and retrospective study investigated the additive value of tumor morphologic features derived from the functional tumor volume (FTV) tumor mask at pre-treatment (T0) and the early treatment time point (T1) in the prediction of pathologic outcomes for breast cancer patients undergoing neoadjuvant chemotherapy.
Methods: A total of 910 patients enrolled in the multicenter I-SPY 2 trial were included. FTV and tumor morphologic features were calculated from the dynamic contrast-enhanced (DCE) MRI.
Background: The risks of postoperative complications in breast cancer patients vary by patient and tumor characteristics. Elevated BMI and invasive lobular carcinoma (ILC) increase risks of surgical complications and positive margins, respectively.
Methods: We retrospectively analyzed patients with BMI ≥30 kg/m from an institutional ILC database.
Objective: Service evaluation of an urban 'Hospital at Home' service which provides care in patients' homes that would traditionally be delivered in the hospital setting.
Design: Retrospective longitudinal review of routinely collected data recorded contemporaneously for clinical use, analysed to elicit utilisation patterns and service impact.
Setting: A paediatric 'Hospital at Home' service delivered across two large acute hospitals, treating a total of 4427 patients across both primary and secondary care in South London from January 2018 to June 2022.
Article Synopsis
- - The study aimed to understand MRI imaging patterns in breast cancer patients undergoing neoadjuvant immunotherapy, particularly focusing on responses to various combinations of chemotherapy and immunotherapy in the I-SPY2 clinical trial.
- - Out of 43 patients analyzed, 44.4% receiving the chemo-immunotherapy experienced increased lymphadenopathy in the first 12 weeks, significantly higher compared to just 6.3% in the control group, with most cases linked to the SD-101 and pembrolizumab treatment.
- - Despite observing increased lymphadenopathy in some patients, this was not associated with a higher incidence of positive lymph nodes at surgery, even as breast tumor sizes decreased over time.