Reviewing the Possible Rare Reasons for Normal Parathyroid Hormone, Vitamin D and Serum Calcium Levels in a Patient With Severe Osteoporosis and Radiologic Parathyroid Adenoma: A Case Report.

Literature evidence describing a seeming de novo occurrence of severe osteoporosis accompanied by the presence of parathyroid adenoma with normal serum parathormone level (PTH), normal serum vitamin D, and serum calcium levels is rare; hence, this case report. In the absence of raised parathormone levels and the demonstration of the presence of parathyroid adenoma, the hypothesis that the authors were left with was that could certain forms of parathyroid adenoma express factors or active substances with severe osteoclastic activity. Or, could certain expressed PTH molecules in parathyroid adenoma scenarios prove difficult to assay using conventional study methods? We have reviewed the literature in a bid to provide answers to these possible uncommon scenarios.

Rhabdomyolysis in a Patient With a Possible Mitochondrial Pathogenic Variant in the Peri-operative Period: A Case Report.

Mitochondrial disorders are often underrecognized as potential causes of rhabdomyolysis, a condition characterized by acute muscle breakdown that can lead to local and potentially systemic complications, with the possibility of being life-threatening. Accounts of rhabdomyolysis as a peri-operative complication associated with mitochondrial disorders are rare; therefore, this study is noteworthy. We describe a case of rhabdomyolysis that occurred during the peri-operative period in a middle-aged male with Charcot-Marie-Tooth (CMT) disease-like peripheral neuropathy.

Reviewing the Rare Association Between Progestogen-only Implant and Pulmonary Embolism in a Woman with Multiple Cardiovascular Risk Factors: A Case Report.

Pulmonary embolism (PE) is a recognized complication of hormonal contraceptive use, but the risk associated with progestogen-only implants in women with multiple cardiovascular (CV) risk factors remains uncertain. We present the case of a woman in her early forties with multiple CV risk factors, including obesity, obstructive sleep apnoea, and hypertension, who developed bilateral PE while using a progestogen-only implant. This case highlights the potential increased risk of PE in women with multiple CV risk factors using progestogen-only implants, warranting further investigation and cautious clinical decision-making.

Investigating the Role of Invasive Streptococcus Constellatus Infection in Severe Systemic Disease Manifestations: A Case Report.

We hope to add to the literature evidence regarding the increasing morbidity associated with an invasive infection by a normal body commensal,  (). An increasing amount of literature documentation of intra- and extracranial disease manifestations following a systemic infection by this micro-organism is noted. We describe the findings of severe, necrotizing right lung disease and possible septic brain emboli in a 54-year-old gentleman in whom microbiological investigations suggest , and mixed anaerobes as possible culprit micro-organisms causing his severe disease state.