Publications by authors named "R M Martinez-Martinez"
Article Synopsis
- COVID-19, caused by the SARS-CoV-2 virus, triggers an uncontrolled immune response that leads to harmful inflammation and lung damage.
- Mast cells (MCs), known for their role in inflammation, are linked to severe COVID-19 cases, particularly through their mediator carboxypeptidase A3 (CPA3).
- The study found that in severe COVID-19 cases, increased CPA3-expressing MCs correlate with the development of pulmonary fibrosis (PF), indicating that excessive inflammation contributes to ongoing tissue damage and impaired healing.
This article provides the foundation for employing nonparametric testing in dental clinical research. To make wise judgments in their research, investigators should learn more about the main nonparametric tests and their particular uses. Biostatistical analysis is essential in dental research; dental research frequently deviates from the assumptions that underpin traditional parametric statistics.
View Article and Find Full Text PDFContext: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries and is strongly associated with several metabolic disorders. Plant-derived bioactive extracts, such as berry extracts, with high antioxidant capacity have been used for the treatment and prevention of this pathology. Moreover, they promote circular economy and sustainability.
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- - In a study of 138 multiple myeloma (MM) patients, researchers explored the benefits of monitoring peripheral residual disease (PRD) in blood instead of relying solely on more invasive bone marrow (BM) assessments.
- - Positive PRD results from next-generation flow (NGF) indicated a significantly higher risk of disease progression/death, and those with undetectable PRD had excellent survival rates.
- - The findings suggest that PRD monitoring is a valuable and less cumbersome method for identifying patients at risk of relapse during maintenance treatment in transplant-eligible MM patients.
Background: Motor and intellectual disabilities (MIDs) represent a great challenge for maintaining general health due to physical and cognitive limitations, particularly in the maintenance and preservation of oral health. Silver nanoparticles (AgNPs) have emerged as a promising therapeutic tool for bacterial control, including oral biofilms; however, knowledge of the bactericidal effectiveness of oral biofilms from patients with MIDs is insufficient. This study aims to determine the antimicrobial effect of AgNPs on different oral biofilms taken from patients with and without MIDs.
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