J Environ Manage
January 2025
Analyzing soil in large and remote areas such as the Amazon River Basin (ARB) is unviable when it is entirely performed by wet labs using traditional methods due to the scarcity of labs and the significant workforce requirements, increasing costs, time, and waste. Remote sensing, combined with cloud computing, enhances soil analysis by modeling soil from spectral data and overcoming the limitations of traditional methods. We verified the potential of soil spectroscopy in conjunction with cloud-based computing to predict soil organic carbon (SOC) and particle size (sand, silt, and clay) content from the Amazon region.
View Article and Find Full Text PDFMelanoma is an aggressive cancer that has attracted attention in recent years due to its high mortality rate of 80%. Damage caused by oxidative stress generated by radical (type I reaction) and singlet oxygen, O (type II reaction) oxidative reactions may induce cancer. Thus, studies that aim to unveil the mechanism that drives these oxidative damage processes become relevant.
View Article and Find Full Text PDFBackground: Adolescence is a crucial phase for developing healthy eating habits with lifelong health implications. Digital interventions, such as smartphone apps and web platforms, have emerged as promising strategies to promote healthy eating habits among adolescents by using behavior change techniques (BCTs). This study aims to systematically review internet-based dietary interventions targeting adolescents, focusing on the analysis of BCTs employed, their delivery modes, and their impact on adolescents' adherence and engagement.
View Article and Find Full Text PDFBackground: The Kerlan-Jobe Orthopedic Clinic (KJOC) Shoulder and Elbow Score is commonly used to assess the functional status of athletes with conditions affecting the shoulder and elbow. However, a Brazilian Portuguese version of the KJOC questionnaire is currently unavailable.
Objectives: This study aimed to develop a Brazilian Portuguese version of the KJOC questionnaire.
Glioblastoma presents a significant treatment challenge due to the blood-brain barrier (BBB) hindering drug delivery, and the overexpression of matrix metalloproteinases (MMPs), which promotes tumor invasiveness. This study introduces a novel nanostructured lipid carrier (NLC) system designed for the delivery of batimastat, an MMP inhibitor, across the BBB and into the glioblastoma microenvironment. The NLCs were functionalized with epidermal growth factor (EGF) and a transferrin receptor-targeting construct to enhance BBB penetration and entrapment within the tumor microenvironment.
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