Publications by authors named "R M Lammers"

Article Synopsis
  • * A retrospective study analyzed 94 pediatric patients with UPJO, comparing the outcomes of LP and RALP, revealing that RALP had a shorter operative time while both procedures had similar hospitalization durations and no intraoperative complications.
  • * Throughout the follow-up period, both surgical techniques demonstrated equal effectiveness and safety, with no recurrence of UPJ obstruction or significant postoperative complications observed in any patients.
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Article Synopsis
  • GBA2 is an enzyme that plays a critical role in breaking down glucosylceramide and has been linked to diseases like Sandhoff and Niemann-Pick type C, as well as parkinsonism.
  • Researchers have developed a specific activity-based probe (ABP) to study GBA2, which shows promise as a tool for visualizing and understanding this enzyme's function and location within cells.
  • The probe, β-d-arabinofuranosyl cyclitol aziridine, selectively binds to GBA2, allowing researchers to distinguish its subcellular localization from that of another enzyme, GBA1, and suggests a pathway for developing new GBA2 inhibitors for future clinical use.
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Undescended testis (UDT, cryptorchidism) is the most frequent genital anomaly in boys. However, its treatment varies widely throughout the world. This second part of our roundtable discussion aims to continue to ask global experts to express their attitudes towards several case scenarios of UDT in order to explore the rationale for their clinical decisions.

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