Statistical method for quantifying mobile phase selectivity in one- and two-dimensional overpressured layer chromatography.

A method for selecting mobile phases for either one-dimensional (1-D) or two-dimensional (2-D) planar chromatography is described and is applied to the separation of steroids by overpressured layer chromatography [Formula: see text] a form of forced-flow thin-layer chromatography [Formula: see text] using both normal- and reversed-phase chromatography. Two metrics are used for evaluating the separation quality of simulated chromatograms for each of 100 (or more) subsets of a set of 30 steroids in each of 15 1-D, and 105 2-D systems. The subsets vary in size between five and 25 steroids.

Kinetic assay of cytotoxic T lymphocyte clones. I. Methodology and data analysis.

A kinetic assay for cytotoxic T lymphocyte (CTL) clones expanded briefly in culture is described. The Hill equation for allosteric kinetics is used to fit curves to dose-response data. In this assay, K0--the target cell concentration required for half-maximal velocity of killing--is determined for clones generated from a population's most frequent CTL precursors.

Statistical analysis of clinical, radiographic, and histologic features of temporomandibular arthropathy.

For a variety of reasons, the past few years have brought about a tremendous emphasis on conditions affecting the temporomandibular joint and associated structures. Although important advances are being made relative to the diagnosis and treatment of these conditions, a myriad of problems remain for the practitioner who tries to sort through the literature or who attends courses in order to determine a means for properly diagnosing and treating these patients. This article attempts to develop correlations between certain clinical and radiographic findings documented by histologic evaluation as a beginning guide to more sound diagnosis.

Statistical comparison of blood glucose as determined by several test-strip procedures and by a hexokinase procedure.

We report a new statistical tool for comparing several dry-reagent strip procedures for whole blood glucose, which produce data in both digital and ordinal form, with results by the well-studied hexokinase-glucose-6-phosphate dehydrogenase procedure coupled to NAD+-NADH. Our use of "ordinal comparison unit" allows for a more equitable comparison of such data. These strip procedures produce biases of -2.