Publications by authors named "R M Kalin"
Carriage of antimicrobial resistance genes in Escherichia coli of bovine origin.
Pol J Vet Sci
December 2024
The present study aimed to search for the presence of the plasmid-mediated antimicrobial resistance genes in 106 Escherichia coli (E. coli) isolates from a total of 240 fresh fecal samples collected from 12 private cattle farms in Bingol province of East Turkey from November 2021 to January 2022. In those colistin-resistant E.
View Article and Find Full Text PDFGroundwater contamination poses significant challenges to public health and sustainable development in Malawi, where approximately 80 % of the population relies on groundwater sources for drinking water. This study investigates the presence and drivers of nitrate and E. coli contamination in groundwater used for drinking.
View Article and Find Full Text PDFPit-latrines are central to achieving UN Sustainable Development Goal 6 (SDG 6) of ensuring "clean water and sanitation for all". Unless safely managed, pit-latrines result in groundwater contamination, which increases morbidity and mortality. Despite this, there have been no long-term spatial projections of future pit-latrine contamination risks.
View Article and Find Full Text PDFArticle Synopsis
- The study highlights how the DNA damage response (DDR) and blood-tumor barrier (BTB) hinder chemotherapy effectiveness in glioblastomas, resulting in frequent relapses.
- It reveals that the interplay between glioblastoma cells and myeloid cells activates GP130 receptor signaling, causing resistance to the chemotherapy drug temozolomide (TMZ) at both genetic and vascular levels.
- The research suggests that blocking GP130 can reduce DDR activity and BTB formation, potentially enhancing the effectiveness of chemotherapy for GBMs with the identification of predictive markers.
Article Synopsis
- Nosema disease, caused by the parasite Nosema ceranae, is a major threat to honey bees, and there's a pressing need for safer treatment options since traditional drugs can be toxic and uncertain in effectiveness.
- The study explored the use of specific egg yolk immunoglobulins (IgY) derived from vaccinated chickens as a potential treatment for Nosema disease, demonstrating high therapeutic effectiveness in both field surveys and controlled laboratory conditions.
- Results showed that IgY significantly reduced the Nosema spore load and the number of infected bees, suggesting that chicken IgYs could serve as a promising, eco-friendly alternative to existing antifungal treatments.