Publications by authors named "R M I Saavedra"

: Despite adverse events following immunization (AEFI) being well described in vaccine trials, there is a need to produce more real-world data on events supposedly attributed to vaccination against COVID-19. This study aims to estimate the prevalence of AEFI in the first dose of COVID-19 vaccines in the state of Brazil and to verify whether such events differ among the types of vaccines offered in this country. : A population-based study using linked administrative data on vaccine registry and adverse events following immunization in 2021 and 2022.

View Article and Find Full Text PDF

The treatment of obesity and cardiovascular disease (CVD) is complex, and a variety of strategies are effective in the lifestyle interventions associated with these disease states. An interdisciplinary approach is the most effective treatment with the best results and outcomes. The lifestyle management of obesity includes interventions in nutrition, exercise, and behavioral health-all key components in managing most chronic illnesses.

View Article and Find Full Text PDF

Each day a venous catheter is retained poses unnecessary safety risks. In a retrospective evaluation of central/peripheral lines in nursing home residents receiving antibiotics, 80% were retained beyond antibiotic treatment end and nearly one third were retained longer than a week. Interventions for timely catheter removal are urgently needed.

View Article and Find Full Text PDF

We study systems of active particles, whose perception is constrained by a vision cone, that are attracted to other particles and repelled from static obstacles. We report a novel self-trapping mechanism: active particles with nonreciprocal attraction form particle chains, which eventually become closed loops that shrink around one or many obstacles. These closed loops act as effective aggregation centers.

View Article and Find Full Text PDF

Objectives: To evaluate the impact of a mobile-app-based central line-associated bloodstream infection (CLABSI) prevention program in nursing home residents with peripherally inserted central catheters (PICCs).

Design: Pre-post prospective cohort study with baseline (September 2015-December 2016), phase-in (January 2017-April 2017), and intervention (May 2017-December 2018). Generalized linear mixed models compared intervention with baseline frequency of localized inflammation/infection, dressing peeling, and infection-related hospitalizations.

View Article and Find Full Text PDF